Cell Biology: Organelles and Functions

Eukaryotic cell organelles, their structures and functions: nucleus, mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomes, and cell membrane transport.

  • Biology
  • 8 entries
  • 1 sections
  • CC0 — public domain

The data

Organelles

NameFunctionStructureKey processes
NucleusStores genetic material (DNA); site of transcription and RNA processingDouble membrane (nuclear envelope) with nuclear pores; contains nucleolus
  • DNA replication
  • Transcription
  • Ribosome subunit assembly in nucleolus
MitochondriaATP production via oxidative phosphorylation; cellular respirationDouble membrane; inner membrane folded into cristae; contains own circular DNA
  • Citric acid cycle (matrix)
  • Electron transport chain (inner membrane)
  • ATP synthesis
Endoplasmic Reticulum (ER)Rough ER: protein synthesis and folding. Smooth ER: lipid synthesis, detoxification, calcium storageNetwork of membranous tubules and sacs; rough ER has ribosomes on surface
  • Protein folding (rough ER)
  • Lipid biosynthesis (smooth ER)
  • Calcium homeostasis
Golgi ApparatusModifies, sorts, and packages proteins for secretion or delivery to other organellesStack of flattened membrane-bound cisternae (cis, medial, trans faces)
  • Glycosylation
  • Protein sorting
  • Vesicle formation for secretion
LysosomesIntracellular digestion; break down waste materials, damaged organelles, and engulfed pathogensMembrane-bound vesicles containing ~60 hydrolytic enzymes (acid hydrolases)
  • Autophagy
  • Phagocytosis
  • Programmed cell death (apoptosis)
Cell Membrane (Plasma Membrane)Selective barrier; regulates transport in/out of cell; cell signaling and adhesionPhospholipid bilayer with embedded proteins (fluid mosaic model); cholesterol for stability
  • Passive diffusion
  • Active transport (pumps)
  • Receptor-mediated signaling
  • Endocytosis/exocytosis
RibosomesProtein synthesis (translation of mRNA into polypeptide chains)Two subunits (large + small); composed of rRNA and proteins; 80S in eukaryotes, 70S in prokaryotes
  • Translation
  • Co-translational translocation (to ER)
CytoskeletonMaintains cell shape; enables cell movement; intracellular transport; cell divisionMicrotubules (tubulin), microfilaments (actin), intermediate filaments
  • Mitosis/meiosis (spindle fibers)
  • Muscle contraction (actin-myosin)
  • Vesicle transport (kinesin/dynein on microtubules)

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Topics

  • biology
  • cell-biology
  • organelles
  • eukaryotic
  • mitochondria
  • nucleus
  • cell-membrane